The precise Etiology of most cases of diabetes is uncertain, although certain contributing factors are as follows:
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Age
Increased age is a factor which gives more possibility than in younger age. This disease may occur at any age, but 80% of cases occur after 50 year, incidences increase as age do in this group.
Poor Diet (Malnutrition Related Diabetes)
Improper nutrition, low protein and fibre intake, high intake of refined products are the expected reasons for developing diabetes.
Stress
Either physical injury or emotional disturbance is frequently blamed as the initial cause of the disease. Any disturbance in Cortiosteroid or ACTH therapy may lead to clinical signs of the diseases.
Hereditary or Inherited Traits
It is strongly believed that is due to some genes which passes from one generation to another. It depends upon closeness of blood relationship as mother is diabetes risk is 2 to 3%, father is diabetic risk is more than the previous case and if both the parents are diabetic, it has much greater risk for diabetes.
Obesity and Fat Distribution
Being overweight means increased insulin resistance, that is if body fat is more than 30%, BMI 25+, waist grith 35 inches in women or 40 inches in males.
Sedentary Lifestyle
People with sedentary lifestyle are more prone to diabetes, when compare to those who exercise thrice a week, are at lesser risk of falling prey to diabetes.
Drug Induced
Clozapine (Clozaril), olanzapine (Zyprexa), risperidone (Risperdal), quetiapine (Seroquel) and ziprasidone (Geodon) are known to induce this lethal disease.
Hypertension
It had been reported in many studies that there is direct relation between high systolic pressure and diabetes.
Infection
Some of the strephylococci are suppose to be responsible factor for infection in pancreas.
Sex
It is commonly seen in elderly especially males but strong evidence of developing diabetes in females with multiple pregnancy has been observed or in females suffering from (PCOS) Polycystic Ovarian Syndrome.
Serum Lipids and Lipoproteins
High triglyceride and cholesterol level in the blood are related to high blood sugars, in some cases it had been studied that risk are involved even with low HDL levels in circulating blood.
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